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Test Code TIU24 Titanium, 24 Hour, Urine


Shipping Instructions


Ship specimen on ice.



Necessary Information


24-Hour volume (in milliliters) is required



Specimen Required


Patient Preparation: High concentrations of gadolinium and iodine are known to interfere with most metal tests. If either gadolinium- or iodine-containing contrast media has been administered, a specimen should not be collected for 96 hours.

 

Supplies: Urine Tubes, 10 mL (T068)

Container/Tube: Plastic, 10-mL urine tube or clean, plastic aliquot container with no metal cap or glued insert

Specimen Volume: 10 mL

Collection Instructions:

1. Collect urine for 24 hours.

2. Leave specimen ambient until received at the collection center.

3. Weigh urine for total volume.

4. Pour off aliquot, freeze, and send to laboratory frozen.

4. See Metals Analysis Specimen Collection and Transport for complete instructions.

Additional Information: See Urine Preservatives-Collection and Transportation for 24-Hour Urine Specimens for multiple collections.


Secondary ID

614613

Useful For

Monitoring exposure and elimination of titanium in a 24 hour urine specimen

Method Name

Triple-Quadrupole Inductively Coupled Plasma-Mass Spectrometry (ICP-MS/MS)

Specimen Type

Urine

Specimen Minimum Volume

0.3 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Urine Frozen 28 days

Reject Due To

  All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.

Reference Values

0-17 years: Not established

≥18 years: <1 mcg/24 h

Interpretation

Elevated concentrations of urinary titanium have been reported after documented exposures.

Method Description

Titanium in urine is analyzed by inductively coupled plasma triple-quadrupole mass spectrometry in mass shift mode using ammonia as a reaction gas, gallium as an internal standard, and a salt matrix calibration. (Unpublished Mayo method)

Day(s) Performed

Wednesday

Report Available

1 to 3 days

Specimen Retention Time

14 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

83018

LOINC Code Information

Test ID Test Order Name Order LOINC Value
TIU24 Titanium, 24 HR, U 29929-7

 

Result ID Test Result Name Result LOINC Value
614613 Titanium, 24 HR, U 29929-7
TIME8 Collection Duration 13362-9
VL73 Urine Volume 3167-4

Urine Preservative Collection Options

Note: The addition of preservative or application of temperature controls must occur within 4 hours of completion of the collection.

Ambient (no additive)

No

Refrigerate (no additive)

No

Frozen (no additive)

Preferred

50% Acetic Acid

OK

Boric Acid

No

Diazolidinyl Urea

No

6M Hydrochloric Acid

No

6M Nitric Acid

No

Sodium Carbonate

No

Thymol

No

Toluene

No