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Test Code SFIGS LAB9766 IgG, Serum

Additional Codes

LAB9766

SFIGS


Specimen Required


Only orderable as part of a profile. For more information see SFIG / Cerebrospinal Fluid IgG Index Profile, Serum and Spinal Fluid.

 

Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Collection Instructions: Within 2 hours of collection, centrifuge and aliquot serum into a plastic vial.


Medical University of South Carolina Note:

DRAW 2 TUBES

Secondary ID

610784

Useful For

Aiding in the diagnosis of multiple sclerosis and other central nervous system inflammatory conditions as a part of a profile

Method Name

Only orderable as part of a profile. For more information see SFIG / Cerebrospinal Fluid IgG Index Profile, Serum and Spinal Fluid.

 

Nephelometry

Specimen Type

Serum
Medical University of South Carolina Note:

DRAW 2 TUBES

Specimen Minimum Volume

0.5 mL

Medical University of South Carolina Note:

SEND 2.0 mL total serum in 2 plastic vials, each vial containing 1.0 mL Serum

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 28 days
  Frozen  28 days
  Ambient  14 days

Reject Due To

Gross hemolysis OK
Gross lipemia Reject
Gross icterus OK

Reference Values

Only orderable as part of a profile. For more information see SFIG / Cerebrospinal Fluid IgG Index Profile, Serum and Spinal Fluid.

 

0-4 months: 100-334 mg/dL

5-8 months: 164-588 mg/dL

9-14 months: 246-904 mg/dL

15-23 months: 313-1,170 mg/dL

2-3 years: 295-1,156 mg/dL

4-6 years: 386-1,470 mg/dL

7-9 years: 462-1,682 mg/dL

10-12 years: 503-1,719 mg/dL

13-15 years: 509-1,580 mg/dL

16-17 years: 487-1,327 mg/dL

≥18 years: 767-1,590 mg/dL

Interpretation

Cerebrospinal fluid (CSF) IgG synthesis rate indicates the rate of increase in the daily CSF production of IgG in milligrams per day. A result greater than 12 mg/24 h is elevated.

 

A CSF IgG index greater than 0.70 is elevated and indicative of increased synthesis of IgG.

Method Description

Serum IgG:

The serum IgG is determined by immunonephelometry.(Instruction manual: Siemens BN II Nephelometer Operations. Siemens, Inc.; V 2.3, 2008; Addendum to the Instruction Manual 2.4 07/2019)

 

Serum albumin:

Serum albumin is measured by colorimetry. The dye, bromocresol green (BCG), is added to serum in an acid buffer. The color intensity of the blue-green albumin-BCG complex is directly proportional to the albumin concentration and is determined photometrically.(Package insert: ALB2. Roche Diagnostics; V 8.0, 06/2024)

Day(s) Performed

Monday through Friday

Report Available

Same day/1 to 2 days

Specimen Retention Time

2 weeks

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

82784

LOINC Code Information

Test ID Test Order Name Order LOINC Value
SFIGS IgG, S 2465-3

 

Result ID Test Result Name Result LOINC Value
IGG_S IgG, S 2465-3
AIGAS IgG/Albumin, S 6782-7
ALBQ Albumin Quotient, CSF/Serum 1756-6