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HelpTest Code LAB9721 FENTU Fentanyl with Metabolite Confirmation, Random, Urine
Additional Codes
FENTU
Useful For
Detection and confirmation of illicit drug use involving fentanyl
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Specimen Type
UrineOrdering Guidance
For situations where chain of custody is required, a Chain of Custody Kit (T282) is available. For chain-of-custody testing, order FENTX / Fentanyl with Metabolite Confirmation, Chain of Custody, Random, Urine.
Additional Testing Requirements
If urine creatinine is required or adulteration of the sample is suspected, the following test should also be ordered, ADULT / Adulterants Survey, Random, Urine.
Specimen Required
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube: Clean, plastic urine collection container
Submission Container/Tube: Plastic, 5-mL tube
Specimen Volume: 5 mL
Collection Instructions:
1. Collect a random urine specimen.
2. No preservative.
Additional Information:
1. No specimen substitutions.
2. STAT requests are not accepted for this procedure.
3. Submitting less than 5 mL will compromise our ability to perform all necessary testing.
Specimen Minimum Volume
2.1 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Urine | Refrigerated (preferred) | 28 days | |
| Frozen | 28 days | ||
| Ambient | 21 days |
Reference Values
Negative
Day(s) Performed
Monday through Friday
CPT Code Information
80354
G0480 (if appropriate)
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| FENTU | Fentanyl w/metabolite Conf, U | 67822-7 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 45530 | Fentanyl by LC-MS/MS | 58381-5 |
| 45531 | Norfentanyl by LC-MS/MS | 58383-1 |
| 45532 | Fentanyl Interpretation | 69050-3 |
Interpretation
The presence of fentanyl above 0.20 ng/mL or norfentanyl above 1.0 ng/mL is a strong indicator that the patient has used fentanyl.
Method Description
The received urine sample is centrifuged, diluted, mixed with internal standard and ammonium hydroxide, and vortexed briefly. It is then extracted using supported liquid extraction, and the extract analyzed by an in-house developed liquid chromatography tandem mass spectrometry method.(Unpublished Mayo method)
Report Available
4 to 7 daysSpecimen Retention Time
14 daysReject Due To
| Gross hemolysis | OK |
| Gross icterus | Reject |
Method Name
Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)
Forms
If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.