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HelpTest Code LAB9673 Thrombospondin Type-1 Domain-Containing 7A Antibodies, Serum
Additional Codes
THSD7A
Specimen Required
Supplies: Sarstedt 5 mL Aliquot Tube (T914)
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container: Plastic vial
Specimen Volume: 1 mL
Collection Information: Centrifuge and aliquot serum into plastic vial within 2 hours of collection.
Secondary ID
607079Useful For
Distinguishing primary from secondary membranous nephropathy cases with antibodies against THSD7A
Method Name
Indirect Immunofluorescence Assay (IFA)
Specimen Type
SerumSpecimen Minimum Volume
0.5 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum | Refrigerated (preferred) | 14 days | |
| Frozen | 14 days | ||
| Ambient | 8 hours |
Reject Due To
| Gross hemolysis | Reject |
| Gross lipemia | OK |
Reference Values
Negative
Interpretation
Therapy outcome can be monitored by measuring the antibody titer. A titer increase, decrease, or disappearance generally precedes a change in clinical status. Thus, the determination of the antibody titer has a high predictive value with respect to clinical remission, relapse, or risk assessment after kidney transplantation.
Method Description
Diluted patient samples are incubated with combinations of substrates. If the reaction is positive, specific antibodies of classes IgA, IgG, and IgM attach to the antigens. In a second step, the attached antibodies are stained with fluorescein-labelled antihuman antibodies and made visible with a fluorescence microscope.(Package insert: Anti-THSD7A IIFT EUROPattern, EUROIMMUN US;V 06/11/2019)
Day(s) Performed
Tuesday
Report Available
3 to 7 daysSpecimen Retention Time
7 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester
CPT Code Information
86255
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| THSD7 | THSD7A Ab, S | 93339-0 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| THSD7 | THSD7A Ab, S | 93339-0 |
Forms
If not ordering electronically, complete, print, and send a Renal Diagnostics Test Request (T830) with the specimen.