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Test Code LAB8678 Cholesteryl Esters, Serum

Additional Codes

CHLE

Useful For

Establishing a diagnosis of lecithin-cholesterol acyltransferase deficiency

 

Evaluating the extent of metabolic disturbance by bile stasis or liver disease

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type

Serum


Specimen Required


Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Collection Instructions: Centrifuge and aliquot serum into plastic vial. Send refrigerated.


Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 7 days
  Frozen  60 days
  Ambient  24 hours

Reference Values

≥18 years: 60-80% of total cholesterol

Reference values have not been established for patients who are less than 18 years of age.

Day(s) Performed

Monday through Friday

CPT Code Information

84311

LOINC Code Information

Test ID Test Order Name Order LOINC Value
CHLE Cholesteryl Esters, S 21197-9

 

Result ID Test Result Name Result LOINC Value
CHLES Cholesteryl Esters, S 21197-9

Interpretation

Persons who have a familial deficiency of lecithin-cholesterol acyltransferase have only 20% or less of serum cholesterol esterified.

Method Description

Free cholesterol reacts with cholesterol oxidase to generate hydrogen peroxide which reacts with 3,5-dimethoxy-N-(2-hydroxy-3-sulfopropyl) aniline sodium (DAOS) and 4-aminoantipyrene to produce a blue pigment. The product is proportional to the serum free cholesterol concentration.(Fujifilm Free Cholesterol E. Fujifilm Wako Pure Chemical Corporation; 12/2021)

Report Available

1 to 3 days

Specimen Retention Time

30 days

Reject Due To

Gross hemolysis Reject
Gross lipemia OK
Gross icterus Reject

Method Name

Enzymatic Colorimetric

Forms

If not ordering electronically, complete, print, and send a Cardiovascular Test Request Form (T724) with the specimen.

Secondary ID

606888