Test Code LAB7555 Alpha-1-Antitrypsin, Random, Feces
Additional Codes
A1AF
Useful For
Diagnosing protein-losing enteropathies, especially when used in conjunction with serum alpha-1-antitrypsin (AAT) levels as a part of AAT clearance studies
Performing Laboratory
Mayo Clinic Laboratories in RochesterSpecimen Type
FecalOrdering Guidance
The preferred test for diagnosing protein-losing enteropathies is A1AFS / Alpha-1-Antitrypsin Clearance, Feces and Serum.
Specimen Required
Supplies:
-Stool container, Small (Random), 4 oz (T288)
-Stool Collection Kit, Random (T635)
Container/Tube: Stool container
Specimen Volume: 5 g
Collection Instructions: Collect a random fecal specimen.
Specimen Minimum Volume
Homogenized Stool: 1 mL
Specimen Stability Information
Specimen Type | Temperature | Time | Special Container |
---|---|---|---|
Fecal | Frozen (preferred) | 14 days | |
Ambient | 14 days | ||
Refrigerated | 14 days |
Reference Values
≤54 mg/dL
Day(s) Performed
Monday through Friday
CPT Code Information
82103
LOINC Code Information
Test ID | Test Order Name | Order LOINC Value |
---|---|---|
A1AF | Alpha-1-Antitrypsin, Random, F | 9407-8 |
Result ID | Test Result Name | Result LOINC Value |
---|---|---|
AAT_F | Alpha-1-Antitrypsin, Random, F | 9407-8 |
Interpretation
Patients with protein-losing enteropathies generally have alpha-1-antitrypsin fecal concentrations over 100 mg/dL.
Borderline elevations above the normal range are equivocal for protein-losing enteropathies.
Method Description
Immunonephelometry quantitates the alpha-1-antitrypsin (AAT) contained in a fecal specimen. In the absence of a timed fecal collection, an AAT fecal concentration will be reported.(Instruction manual: Siemens Nephelometer II Operations. Siemens, Inc; Version 2.3, 2008; Addendum to the Instruction Manual 2.3, 08/2017)
Report Available
1 to 3 daysSpecimen Retention Time
14 days; supernatant aliquot only, the feces are discarded after processingReject Due To
Feces collected in any preservative or fixative | Reject |
Method Name
Nephelometry