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Test Code LAB7555 Alpha-1-Antitrypsin, Random, Feces

Additional Codes

A1AF

Useful For

Diagnosing protein-losing enteropathies, especially when used in conjunction with serum alpha-1-antitrypsin (AAT) levels as a part of AAT clearance studies

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type

Fecal


Ordering Guidance


The preferred test for diagnosing protein-losing enteropathies is A1AFS / Alpha-1-Antitrypsin Clearance, Feces and Serum.



Specimen Required


Supplies:

-Stool container, Small (Random), 4 oz (T288)

-Stool Collection Kit, Random (T635)

Container/Tube: Stool container

Specimen Volume: 5 g

Collection Instructions: Collect a random fecal specimen.


Specimen Minimum Volume

Homogenized Stool: 1 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Fecal Frozen (preferred) 14 days
  Ambient  14 days
  Refrigerated  14 days

Reference Values

≤54 mg/dL

Day(s) Performed

Monday through Friday

CPT Code Information

82103

LOINC Code Information

Test ID Test Order Name Order LOINC Value
A1AF Alpha-1-Antitrypsin, Random, F 9407-8

 

Result ID Test Result Name Result LOINC Value
AAT_F Alpha-1-Antitrypsin, Random, F 9407-8

Interpretation

Patients with protein-losing enteropathies generally have alpha-1-antitrypsin fecal concentrations over 100 mg/dL.

 

Borderline elevations above the normal range are equivocal for protein-losing enteropathies.

Method Description

Immunonephelometry quantitates the alpha-1-antitrypsin (AAT) contained in a fecal specimen. In the absence of a timed fecal collection, an AAT fecal concentration will be reported.(Instruction manual: Siemens Nephelometer II Operations. Siemens, Inc; Version 2.3, 2008; Addendum to the Instruction Manual 2.3, 08/2017)

Report Available

1 to 3 days

Specimen Retention Time

14 days; supernatant aliquot only, the feces are discarded after processing

Reject Due To

Feces collected in any preservative or fixative Reject

Method Name

Nephelometry

Secondary ID

182