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HelpTest Code LAB7523 Manganese, Serum
Additional Codes
MNS
Useful For
Monitoring manganese exposure using serum specimens
Nutritional monitoring
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Specimen Type
SerumSpecimen Required
Patient Preparation: High concentrations of gadolinium and iodine are known to potentially interfere with most inductively coupled plasma mass spectrometry-based metal tests. If either gadolinium- or iodine-containing contrast media has been administered, a specimen should not be collected for 96 hours
Supplies:
-Metal Free B-D Tube (No Additive), 6 mL (T184)
-Metal Free Specimen Vial (T173)
Collection Container/Tube: 6 mLPlain, royal blue-top Vacutainer plastic trace element blood collection tube
Submission Container/Tube: 7-mL Mayo metal-free, screw-capped, polypropylene vial
Specimen Volume: 1.6 mL
Collection Instructions: See Metals Analysis Specimen Collection and Transport for complete instructions.
Specimen Minimum Volume
0.3 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum | Refrigerated (preferred) | 28 days | METAL FREE |
| Ambient | 28 days | METAL FREE | |
| Frozen | 28 days | METAL FREE |
Special Instructions
Reference Values
0-17 years: Not established
≥18 years: 0.4-0.9 ng/mL
Day(s) Performed
Monday through Friday
CPT Code Information
83785
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| MNS | Manganese, S | 5683-8 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 8413 | Manganese, S | 5683-8 |
Interpretation
Serum manganese results above the reference values suggest recent exposure. Serum concentrations in combination with brain magnetic resonance imaging scans and neurological assessment may be used to detect excessive exposure.
Method Description
The metal of interest is analyzed by triple-quadrupole inductively coupled plasma mass spectrometry.(Unpublished Mayo method)
Report Available
1 to 4 daysSpecimen Retention Time
14 daysReject Due To
| Gross hemolysis | Reject |
| Gross lipemia | OK |
| Gross icterus | OK |
Method Name
Triple-Quadrupole Inductively Coupled Plasma-Mass Spectrometry (ICP-MS/MS)