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Test Code LAB7518 Flecainide, Serum

Additional Codes

FLEC

Useful For

Optimizing flecainide dosage

 

Assessing flecainide toxicity

 

Monitoring compliance

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type

Serum Red


Specimen Required


Supplies: Sarstedt Aliquot Tube, 5 mL (T914)

Collection Container/Tube: Red top (serum gel/SST are not acceptable)

Submission Container/Tube: Plastic vial

Specimen Volume: 1.5 mL

Collection Instructions:

1. Draw blood immediately before next scheduled dose.

2. Centrifuge and aliquot serum into a plastic vial within 2 hours of collection.


Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Red Refrigerated (preferred) 28 days
  Ambient  28 days
  Frozen  28 days

Reference Values

Trough Value

0.2-1.0 mcg/mL: Therapeutic concentration

>1.0 mcg/mL: Toxic concentration

Day(s) Performed

Monday through Friday

CPT Code Information

80181

LOINC Code Information

Test ID Test Order Name Order LOINC Value
FLEC Flecainide, S 3638-4

 

Result ID Test Result Name Result LOINC Value
9243 Flecainide, S 3638-4

Interpretation

Flecainide is most effective in premature ventricular contractions suppression at serum concentrations in the range of 0.2 to 1.0 mcg/mL.

 

Serum concentrations above 1.0 mcg/mL are associated with a high rate of cardiac adverse experiences such as conduction defects or bradycardia.

Method Description

Protein is precipitated from serum and following centrifugation the supernatant is diluted and analyzed by liquid chromatography tandem mass spectrometry.(Unpublished Mayo method)

Report Available

2 to 5 days

Specimen Retention Time

14 days

Reject Due To

Gross hemolysis OK
Gross lipemia OK
Gross icterus OK

Method Name

Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)

Secondary ID

9243

Forms

If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.