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Test Code LAB7480 Fibrinogen Antigen, Plasma

Additional Codes

FIBAG

Useful For

Evaluation of fibrinogen deficiency

 

Measuring fibrinogen in patients with elevated plasma levels of fibrin degradation products, patients receiving heparin, and in patients with antibodies to thrombin (following surgical use of topical bovine thrombin)

 

Identifying afibrinogenemia, hypofibrinogenemia, and dysfibrinogenemia when ordered in combination with fibrinogen activity (FIBTP / Fibrinogen, Plasma)

Method Name

Immunoturbidimetric

Specimen Type

Plasma Na Cit


Specimen Required


Supplies: Sarstedt Aliquot Tube 5 mL (T914)

Collection Container/Tube: Light-blue top (3.2% sodium citrate at 9:1 ratio)

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Collection Instructions: Centrifuge and aliquot plasma into plastic vial. Send refrigerated.


Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Plasma Na Cit Refrigerated (preferred) 14 days
  Frozen  30 days
  Ambient  72 hours
Medical University of South Carolina Note:

On-campus collections: Send in plastic vial, Refrigerated.
 
Off-campus collections: Centrifuge and aliquot within 1 hour. Specimen to be stored/transported at Refrigerated temp. 

Reject Due To

Gross hemolysis Reject
Gross lipemia Reject
Gross icterus Reject

Reference Values

≥18 years: 196-441 mg/dL

Reference values have not been established for patients that are less than 18 years of age.

Interpretation

This method measures the total amount of fibrinogen protein (ie, fibrinogen antigen) present in the plasma.

 

Adequate fibrinogen antigen levels in a context of low fibrinogen activity suggests a dysfibrinogenemia.

 

Fibrinogen antigen levels lower than 100 mg/dL are associated with an increased risk of bleeding.

Method Description

The K-ASSAY Fibrinogen test analyzes the quantitative determination of fibrinogen in human plasma by immunoturbidimetric analysis. Samples and antibody reagent are automatically pipetted into individual cuvettes. Following an initial incubation and measurement of sample blank, antiserum is added to the cuvettes. The sample (antigen) solution and antiserum are then mixed in the reaction cuvettes. Insoluble antigen-antibody complexes form. The immune complexes cause an increase in light scattering, which correlates with the concentration of plasma fibrinogen. The absorbance of the solution is measured.(Package insert: K-ASSAY Fibrinogen. Kamiya Biomedical Company; 03/2023)

Day(s) Performed

Monday through Friday

Report Available

1 to 3 days

Specimen Retention Time

7 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

85385

LOINC Code Information

Test ID Test Order Name Order LOINC Value
FIBAG Fibrinogen Antigen, P 3256-5

 

Result ID Test Result Name Result LOINC Value
FIBAG Fibrinogen Antigen, P 3256-5

Secondary ID

606887