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HelpTest Code LAB7478 Selenium, Serum
Additional Codes
SES
Useful For
Monitoring selenium replacement therapy
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Specimen Type
SerumSpecimen Required
Patient Preparation: High concentrations of gadolinium, iodine, and barium are known to potentially interfere with most inductively coupled plasma mass spectrometry-based metal tests. If either gadolinium-, iodine-, and barium containing contrast media has been administered, a specimen should not be collected for 96 hours.
Supplies:
-Metal Free Specimen Vial (T173)
-Metal Free B-D Tube (No Additive), 6 mL (T184)
Collection Container/Tube: 6-mL Plain, royal blue-top Vacutainer plastic trace element blood collection tube
Submission Container/Tube: 7-mL Metal-free, screw-capped, polypropylene vial
Specimen Volume: 0.8 mL serum
Collection Instructions:
1. Allow the specimen to clot for 30 minutes; then centrifuge the specimen to separate serum from the cellular fraction.
2. Remove the stopper. Carefully pour specimen into a metal-free, polypropylene vial, avoid transferring the cellular components of blood. Do not insert a pipette into the serum to accomplish transfer, and do not ream the specimen with a wooden stick to assist with serum transfer.
3. See Metals Analysis Specimen Collection and Transport for complete instructions.
On-campus collections: Tube to 99 or deliver to University Extension Hospital Room EH318. Send in 7-mL Mayo metal-free, screw-capped, polypropylene vial (T173, Refrigerated.
Off-campus collections: Centrifuge and aliquot after 30 minutes. Specimen to be stored/transported at Refrigerated temp.
Specimen Minimum Volume
Serum: 0.2 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum | Refrigerated (preferred) | 28 days | METAL FREE |
| Ambient | 28 days | METAL FREE | |
| Frozen | 28 days | METAL FREE |
Special Instructions
Reference Values
0-2 months: 45-90 mcg/L
3-6 months: 50-120 mcg/L
7-9 months: 60-120 mcg/L
10-12 months: 70-130 mcg/L
13 months-17 years: 70-150 mcg/L
≥18 years: 110-165 mcg/L
Day(s) Performed
Monday through Saturday
CPT Code Information
84255
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| SES | Selenium, S | 5724-0 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 9765 | Selenium, S | 5724-0 |
Interpretation
Selenium accumulates in biological tissue. The normal concentration in adult human serum is 110 to 165 mcg/L. Optimal selenium concentration is age dependent (see Reference Values); children require less circulating selenium than adults.
In the state of selenium deficiency associated with loss of glutathione peroxidase activity, the serum concentration is usually below 40 mcg/L.
Method Description
The metal analytes of interest are analyzed by triple-quadrupole inductively coupled plasma mass spectrometry.(Unpublished Mayo method)
Report Available
1 to 3 daysSpecimen Retention Time
14 daysReject Due To
| Gross hemolysis | OK |
| Gross lipemia | OK |
| Gross icterus | OK |
Method Name
Triple-Quadrupole Inductively Coupled Plasma Mass Spectrometry (ICP-MS/MS)
Secondary ID
9765Forms
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