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Test Code LAB686 Felbamate (Felbatol), Serum

Additional Codes

FELBA

Useful For

Determining whether a poor therapeutic response is attributable to noncompliance or lack of drug effectiveness

 

Monitoring changes in serum concentrations resulting from interactions with coadministered drugs such as barbiturates and phenytoin

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type

Serum


Specimen Required


Supplies: Sarstedt Aliquot Tube 5 mL (T914)

Container/Tube:

Preferred: Red top

Acceptable: Serum gel

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Collection Instructions:

1. Draw blood immediately before next scheduled dose.

2. Within 2 hours of collection, centrifuge the specimen.

3. For red-top tubes, immediately aliquot serum into a plastic vial.

4. For serum-gel tubes, aliquot serum into a plastic vial within 24 hours of collection.


Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 28 days
  Ambient  28 days
  Frozen  28 days

Reference Values

30.0-80.0 mcg/mL

CPT Code Information

80167

LOINC Code Information

Test ID Test Order Name Order LOINC Value
FELBA Felbamate (Felbatol), S 6899-9

 

Result ID Test Result Name Result LOINC Value
80782 Felbamate (Felbatol), S 6899-9

Interpretation

Optimal response to felbamate is associated with serum concentrations of 30 mcg/mL to 80 mcg/mL.

 

Toxic serum concentrations for felbamate have been established at concentrations greater than 100 mcg/mL.

Report Available

Same day/1 to 3 days

Specimen Retention Time

14 days

Reject Due To

Gross hemolysis OK
Gross lipemia OK
Gross icterus OK

Method Name

Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)

Day(s) Performed

Monday, Wednesday, Friday

Forms

If not ordering electronically, complete, print, and send 1 of the following forms with the specimen:

-Neurology Specialty Testing Client Test Request (T732)

-Therapeutics Test Request (T831)

Method Description

Samples are diluted and extracted online by high turbulence liquid chromatography with detection by tandem mass spectrometry.(Unpublished Mayo method)

Secondary ID

80782