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Test Code LAB581 Zinc, Serum

Additional Codes

ZN_S


Specimen Required


Patient Preparation: High concentrations of gadolinium, iodine, and barium are known to interfere with most metal tests. If gadolinium-, iodine, or barium-containing contrast media has been administered, the specimen should not be collected for 96 hours.

Supplies:

-Metal Free Specimen Vial (T173)

-Metal Free B-D Tube (No Additive), 6 mL (T184)

Collection Container/Tube: 6-mL Plain, royal blue-top Vacutainer plastic trace element blood collection tube

Submission Container/Tube: 7-mL Mayo metal-free, screw-capped, polypropylene vial

Specimen Volume: 0.8 mL

Collection Instructions:

1. This specimen must always be drawn first.

2. Do not collect specimen from a line.

3. Allow the specimen to clot for 30 minutes; then centrifuge the specimen to separate serum from the cellular fraction. Serum must be removed from cellular fraction within 4 hours of specimen collection. Avoid hemolysis.

4. Remove the stopper. Carefully pour specimen into a Mayo metal-free, polypropylene vial, avoiding transfer of the cellular components of blood. Do not insert a pipet into the serum to accomplish transfer, and do not ream the specimen with a wooden stick to assist with serum transfer.

5. See Metals Analysis Specimen Collection and Transport for complete instructions.


Secondary ID

7735

Useful For

Detecting zinc deficiency

Method Name

Dynamic Reaction Cell-Inductively Coupled Plasma-Mass Spectrometry (DRC-ICP-MS)

Specimen Type

Serum

Specimen Minimum Volume

0.2 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 28 days METAL FREE
  Ambient  28 days METAL FREE
  Frozen  28 days METAL FREE

Reject Due To

Gross hemolysis Reject
Gross lipemia OK
Gross icterus OK

Reference Values

0-10 years: 60-120 mcg/dL

11-17 years: 66-110 mcg/dL

≥18 years: 60-106 mcg/dL

Interpretation

Normal serum zinc levels are from 66 to 106 mcg/dL in adults.

 

Burn patients with acrodermatitis may have zinc levels as low as 40 mcg/dL; these patients respond quickly to zinc supplementation.

 

An elevated serum zinc concentration is of minimal clinical interest.

Method Description

The metal of interest is analyzed by inductively coupled plasma mass spectrometry.(Unpublished Mayo method)

Day(s) Performed

Monday through Saturday

Report Available

1 to 3 days

Specimen Retention Time

14 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

84630

LOINC Code Information

Test ID Test Order Name Order LOINC Value
ZN_S Zinc, S 5763-8

 

Result ID Test Result Name Result LOINC Value
7735 Zinc, S 5763-8

Forms

If not ordering electronically, complete, print, and send General Test Request (T239) with the specimen.