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Test Code LAB406 Magnesium, 24 Hour, Urine

Important Note

MAGU

Useful For

Assessing the cause of abnormal serum magnesium concentrations using a 24-hour urine collection

 

Determining whether nutritional magnesium loads are adequate

 

Calculating urinary calcium oxalate and calcium phosphate supersaturation and assessing kidney stone risk

Method Name

Colorimetric Endpoint Assay

Specimen Type

Urine


Necessary Information


Specimen volume in milliliters and duration are required.



Specimen Required


Supplies: Sarstedt 5 mL Aliquot Tube (T914)

Collection Container/Tube: 24-hour graduated urine container with no metal cap or glued insert

Submission Container/Tube: Plastic, 5 mL tube or a clean, plastic urine container with no metal cap or glued insert

Specimen Volume: 4 mL

Collection Instructions:

1. Collect urine for 24 hours.

2. Refrigerate specimen within 4 hours of completion of 24-hour collection.

Additional Information: See Urine Preservatives-Collection and Transportation for 24-Hour Urine Specimens for multiple collections.


Specimen Minimum Volume

1 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Urine Refrigerated (preferred) 14 days
  Frozen  30 days
  Ambient  72 hours

Reject Due To

All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.

Reference Values

51-269 mg/24 hours

Reference values have not been established for patients <18 years and >83 years of age.

Interpretation

Urinary magnesium excretion should be interpreted in concert with serum concentrations.

 

In the presence of hypomagnesemia, a 24-hour urine magnesium greater than 24 mg/day or fractional excretion greater than 0.5% suggests renal magnesium wasting. Lower values suggest inadequate magnesium intake and/or gastrointestinal losses.

 

In the presence of hypermagnesemia, urinary magnesium levels provide an indication of current magnesium intake.

 

Lower urinary magnesium excretion increases urinary calcium oxalate and calcium phosphate supersaturation and could contribute to kidney stone risk.

Method Description

In alkaline solution, magnesium forms a purple complex with xylidyl blue, diazonium salt. The magnesium concentration is measured photometrically via the decrease in xylidyl blue absorbance.(Package insert: Roche MG2 kit. Roche Diagnostics;  V8.0 01/2020)

Specimen Retention Time

7 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

83735

LOINC Code Information

Test ID Test Order Name Order LOINC Value
MAGU Magnesium, 24 HR, U 24447-5

 

Result ID Test Result Name Result LOINC Value
MG24 Magnesium, 24 HR, U 24447-5
TM115 Collection Duration 13362-9
VL111 Urine Volume 3167-4

Urine Preservative Collection Options

Note: The addition of preservative or application of temperature controls must occur within 4 hours of completion of the collection.

Ambient

OK

Refrigerate

Preferred

Frozen

OK

50% Acetic Acid

OK

Boric Acid

OK

Diazolidinyl Urea

OK

6M Hydrochloric Acid

OK

6M Nitric Acid

No

Sodium Carbonate

No

Thymol

OK

Toluene

No

Forms

If not ordering electronically, complete, print, and send a Renal Diagnostics Test Request (T830) with the specimen.

Secondary ID

610768

Day(s) Performed

Monday through Sunday

Report Available

Same day/1 to 3 days