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Test Code LAB23 Digoxin

Additional Codes

DIG

Notes:

Collect specimen 12 hours after oral administration or 6 hours after IV administration.

Collection:

Specimen: Blood 

Preferred: Lt Green w/ Gel - Li Hep

Acceptable: SST or Red Top

Specimen Volume: 5 mL; Minimum 1.0 mL

 

Pediatric Collection:

One Lt Green w/ Gel - Li Hep, SST, or Red Top microtainer filled to 500 uL.

Stability:

Separate plasma/serum from gel/cells within 4 hours of collection. Once separated from cells/gel:

Ambient: 8 Hours

Refrigerated (preferred): 2 Days

Frozen: 2 Weeks

 

Turnaround Time (TAT):

STAT: 1 HOUR

Routine: 4 HOURS

Test Availability:

Daily / 24 Hours / Available STAT

Performing Laboratory Section:

Chemistry / UMC MAIN LABORATORY

Reference Interval:

Therapeutic: 0.8 - 2.0 ng/mL

 

Toxic: > 2.4 ng/mL

Interpretive Data:

The therapeutic range suggested for efficacy in patients with congestive heart failure is 0.5-1.0 ng/ml. The traditional therapeutic range of 0.8-2.0 ng/ml was originally developed to classify digoxin toxicity. References: Pharmacotherapy 1999;19(10):1123-1126.JAMA 2003; 289(7):871-878.