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HelpTest Code LAB2118 Soluble Transferrin Receptor (sTfR), Serum
Additional Codes
STFR
Useful For
Evaluation of suspected iron deficiency in patients who may have inflammation, infection, or chronic disease and other conditions in which ferritin concentration does not correlate with iron status, including:
-Cystic fibrosis patients who frequently have inflammation or infections(2-3)
-Evaluating insulin-dependent diabetics who may have iron-deficiency resulting from gastric autoimmunity and atrophic gastritis(4)
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Specimen Type
SerumSpecimen Required
Supplies: Sarstedt Aliquot Tube 5 mL (T914)
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 1 mL
Collection Instructions:
1. Serum gel tubes should be centrifuged within 2 hours of collection.
2. Red-top tubes should be centrifuged, and the serum aliquoted into a plastic vial within 2 hours of collection.
Specimen Minimum Volume
0.25 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum | Frozen (preferred) | 90 days | |
| Refrigerated | 7 days | ||
| Ambient | 72 hours |
On-campus collections: Tube to 99 or deliver to University Extension Hospital Room EH318
Submission Container/Tube: Plastic vial, Frozen
Off-campus collections: Centrifuge and aliquot within 2 hours. Specimen to be stored/transported FROZEN.
Reference Values
1.8-4.6 mg/L
It is reported that African Americans may have slightly higher values.
Day(s) Performed
Monday through Sunday
CPT Code Information
84238
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| STFR | Soluble Transferrin Receptor (sTfR) | 30248-9 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| STFR | Soluble Transferrin Receptor (sTfR) | 30248-9 |
Interpretation
Soluble transferrin receptor (sTfR) concentrations are inversely related to iron status; sTfR elevates in response to iron deficiency and decreases in response to iron repletion.
Method Description
Latex-bound anti-sTfR antibodies react with the antigen in the sample to form an antigen/antibody complex. Following agglutination, the complex is measured turbidimetrically on a Roche P Modular.(Package insert: The Tina-quant Soluble Transferrin Receptor Immunoturbidimetric assay for the in vitro quantitative determination of soluble transferrin receptor. Roche Corporation; V 2, 01/2021)
Report Available
Same day/1 to 2 daysSpecimen Retention Time
1 weekReject Due To
| Gross hemolysis | Reject |
Method Name
Immunoturbidimetric Assay