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Test Code LAB2110 Poliovirus (Types 1, 3) Antibodies, Neutralization

Additional Codes

FPOLO


Specimen Required


Specimen Type: Serum

Collection Container/Tube:

Preferred: Red top

Acceptable: Serum gel

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Collection Instructions:

1. Centrifuge and aliquot 1 mL of serum into a plastic vial.

2. Ship refrigerated.


Secondary ID

75165

Method Name

Culture/Neutralization

Specimen Type

Serum

Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Refrigerated (preferred) 14 days
  Frozen  30 days
  Ambient  5 days
Medical University of South Carolina Note:

On-campus collections: Tube to 99 or deliver to University Extension Hospital Room EH318 
Send in plastic vial, Refrigerated
 
Off-campus collections: 
Centrifuge and aliquot within 2 hours.
Specimen to be stored/transported Refrigerated

Reference Values

Polio 1 Titer: <1:8

Polio 3 Titer: <1:8

Day(s) Performed

Monday and Thursday

Report Available

1 to 10 days

Performing Laboratory

Quest Diagnostics

CPT Code Information

86382 x 2

LOINC Code Information

Test ID Test Order Name Order LOINC Value
FPOLO Poliovirus (Types 1, 3) Ab, Neut 68320-1

 

Result ID Test Result Name Result LOINC Value
Z4806 Polio 1 Titer 22446-9
Z4807 Polio 3 Titer 22450-1

Reject Due To

All specimens will be evaluated at the performing laboratory for test suitability.

Interpretation

The presence of neutralizing serum antibodies (titers 1:8 up to >1:128) against polioviruses implies lifelong immunity. Some persons without detectable titers (<1:8) may also be immune as demonstrated by elicitation of a secondary-type serum antibody response upon rechallenge with live polio vaccine.