Test Code LAB15448 Chronic Hepatitis Panel

Includes:

Hepatitis B Surface Antibody, Hepatitis B Surface Antigen Screen, Hepatitis B Core Total Antibody and Hepatitis C Virus Antibody Screen

Specimen: Blood

Container: Serum Separator or Plain Red Tube

Volume: 7 mL; Minimum 3 mL

Pediatric Collection:

Three Gold or Red microtainers filled to 600 uL.

Once serum is separated from cells:

Ambient: 8 Hours

Refrigerated (preferred): 1 Week

Frozen: 2 Weeks

STAT: 2 HOURS

Routine: 3 HOURS

24 hours a day / 7 Days a week

Chemistry / UMC MAIN LABORATORY

Hepatitis B Surface Antibody: Non-reactive

Hepatitis B Surface Antigen: Non-reactive

Hepatitis B Core Total Antibody: Non-reactive

Hepatitis C Virus Antibody Screen: Non-reactive

Hepatitis B Surface Antibody
A negative value indicates the anti-HBs level is below 8 mIU/mL and the patient is considered not to have protective immunity to HBV infection. A positive test indicates the patient has anti-HBs equal to or greater than 12 mIU/mL. This cutoff is the accepted level for protective immunity to hepatitis B as defined by the World Health Organization level and in accordance with CDC guidelines. Interpretation information is based on the Abbott product literature. Results by other assay methods cannot be used interchangeably with the Abbott assay values.
Result	Interpretation
Nonreactive	Individual is considered not immune to HBV infection.
Grayzone	The immune status of the individual should be further assessed by considering other factors, such as clinical status, follow-up testing, associated risk factors, and the use of additional diagnostic information.
Reactive	Individual is considered immune to HBV infection.

Hepatitis B Core Total Antibody
The anti-HBc Total assay detects both IgM and IgG anti-HBc responses. Interpretation information is based on the Abbott product literature. Results by other assay methods cannot be used interchangeably with the Abbott assay values.
Result	Interpretation
Nonreactive	Anti-HBc antibodies not detected. It is possible that the individual is not infected with HBV.
Reactive	Anti-HBc antibodies were detected in the sample which suggests either on-going or previous HBV infection.

Hepatitis B Surface Antigen Screen
Interpretation information is based on the Abbott product literature. Results by other assay methods cannot be used interchangeably with the Abbott assay values.
Result	Interpretation
Nonreactive	Specimen considered negative for HBsAg.
Reactive	Specimen considered repeatedly reactive; will be confirmed using the ALINITY HBsAg Qualitative Confirmatory assay.

Hepatitis C Virus Antibody Screen
Interpretation information is based on the Abbott product literature. Results by other assay methods cannot be used interchangeably with the Abbott assay values.
Result	Interpretation
Nonreactive	Antibodies to HCV not detected; does not exclude the possibility of exposure to HCV.
Equivocal	Antibodies to HCV may or may not be present; a reflexive HCV RNA test will be performed on the specimen to determine infection status (current or resolved).
Reactive	Presumptive evidence of antibodies to HCV; a reflexive HCV RNA test will be performed on the specimen to determine infection status (current or resolved).