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Test Code LAB13076 Breast Carcinoma-Associated Antigen, Serum

Additional Codes

C2729

CA 27.29

CA 27-29

CA2729

Secondary ID

606583

Useful For

Aiding in the management of breast cancer in patients with metastatic disease by monitoring the progression or regression of disease in response to treatment

 

Serial testing in women with prior stage II or III breast cancer who are clinically free of disease

 

May be useful for predicting early recurrence of disease in women with treated carcinoma of the breast

 

This test is not useful for screening women for or diagnosis of carcinoma of the breast.

Method Name

Chemiluminometric Immunoassay

Specimen Type

Serum


Specimen Required


Supplies: Sarstedt Aliquot Tube, 5 mL (T914)

Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 0.5 mL

Collection Instructions:

1. Within 2 hours of collection, centrifuge and aliquot serum into a plastic vial. Specimens that have not been aliquoted will be canceled.

2. Send refrigerated.


Specimen Minimum Volume

0.25 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 7 days
  Frozen  90 days
  Ambient  4 days

Reject Due To

Gross hemolysis Reject
Gross lipemia OK

Reference Values

Males

≥18 years: ≤38.0 U/mL (use not defined)

Females

≥18 years: ≤38.0 U/mL

Reference values have not been established for patients who are younger than 18 years of age.

Serum markers are not specific for malignancy, and values may vary by method.

Interpretation

Increased levels of cancer-associated antigen (CA 27.29) (>38 U/mL) may indicate recurrent disease in a woman with treated breast carcinoma and may be useful as an indication that additional tests or procedures should be performed to confirm recurrence.

Method Description

Cancer antigen (CA) 27.29 is measured using an automated, competitive, chemiluminescent immunoassay. The signal (Lite) reagent is a monoclonal antibody specific for CA 27.29, which is labeled with acridinium ester. Purified CA 27.29 antigen attached to paramagnetic particles (solid phase) competes with the antigen in the specimen for binding to the monoclonal antibody. An inverse relationship exists between the amount of CA 27.29 in the patient specimen and the amount of relative light units detected by the system.(Package insert: Advia Centaur XPT CA 27.29. Siemens Healthcare Diagnostics Inc.; 11206409_EN Rev. 22, 10/2022)

Day(s) Performed

Monday through Friday

Report Available

Same day/1 to 3 days

Specimen Retention Time

3 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

86300

LOINC Code Information

Test ID Test Order Name Order LOINC Value
C2729 Breast Carcinoma Assoc Ag(CA 27.29) 17842-6

 

Result ID Test Result Name Result LOINC Value
C2729 Breast Carcinoma Assoc Ag(CA 27.29) 17842-6

Forms

If not ordering electronically, complete, print, and send 1 of the following forms with the specimen:

-General Request (T239)

-Oncology Test Request (T729)