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Test Code LAB130 Vitamin E, Serum

Additional Codes

VITE

Secondary ID

42358

Useful For

Monitoring of Vitamin E supplementation/treatment

 

Potentially detecting Vitamin E overdoses

Method Name

Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)

Specimen Type

Serum


Shipping Instructions


Ship specimen in amber vial to protect from light.



Specimen Required


Patient Preparation: Patient should fast overnight (12-14 hours); infants should have specimen collected before next feeding.

Supplies: Amber Frosted Tube, 5 mL (T915)

Collection Container/Tube:

Preferred: Red top

Acceptable: Serum gel

Submission Container/Tube: Amber vial

Specimen Volume: 0.5 mL

Collection Instructions: Centrifuge and aliquot serum into light protected plastic vial within 2 hours of collection.


Specimen Minimum Volume

0.25 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 44 days LIGHT PROTECTED
  Frozen  44 days LIGHT PROTECTED
  Ambient  7 days LIGHT PROTECTED
Medical University of South Carolina Note:

    On-campus collections: Tube to 99 or deliver to University Extension Hospital Room EH318 
Submission Container/Tube: Amber vial, Refrigerated
 
Off-campus collections: Protect from light
Centrifuge and aliquot within 2 hours. Submission Container/Tube: Amber vial
Specimen to be stored/transported Refrigerated

Reject Due To

Gross hemolysis Reject
Gross lipemia Reject
Gross icterus OK

Reference Values

0-17 years: 3.8-18.4 mg/L

≥18 years: 5.5-17.0 mg/L

Interpretation

Vitamin E concentrations within the healthy reference population range usually indicate adequate Vitamin A stores.

 

The rare occurrence of low Vitamin A levels might correlate with potential deficiency and investigation of potential fat malabsorptions should be considered.

 

Conversely, Vitamin E concentrations significantly above the upper healthy reference population range might indicate that Vitamin E intake exceeds the tolerable upper daily intake level(s).

Method Description

Deuterated vitamin E (d6-alpha-tocopherol) is added to serum as an internal standard. Vitamin E (alpha-tocopherol) and the deuterated internal standard are extracted from the specimens and analyzed by liquid chromatography-tandem mass spectrometry.(Unpublished Mayo method)

Day(s) Performed

Sunday through Friday

Report Available

3 to 5 days

Specimen Retention Time

14 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

CPT Code Information

84446

LOINC Code Information

Test ID Test Order Name Order LOINC Value
VITE Vitamin E, S 1823-4

 

Result ID Test Result Name Result LOINC Value
2350 A-Tocopherol, Vitamin E 1823-4

Forms

If not ordering electronically, complete, print, and send a General Request (T239) with the specimen.