Home
HelpTest Code LAB12985 Histoplasma and Blastomyces Antigen, Enzyme Immunoassay, Urine
Additional Codes
UHBAG
Specimen Required
Supplies: Sarstedt Aliquot tube, 5 mL (T914)
Container/Tube: Plastic vial
Specimen Volume: 3 mL
Collection Instructions:
1. Collect a random urine specimen, with no preservative.
2. Do not centrifuge to remove particulates.
Secondary ID
621248Useful For
Diagnosing Histoplasma capsulatum or Blastomyces dermatitidis infection without differentiation between the organisms
Monitor antigen levels following initiation of antifungal treatment
Method Name
Enzyme Immunoassay (EIA)
Specimen Type
UrineSpecimen Minimum Volume
2.5 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Urine | Refrigerated (preferred) | 14 days | |
| Frozen | 28 days | ||
| Ambient | 7 days |
Reject Due To
| Gross hemolysis | Reject |
| Turbid Colored |
Reject |
Reference Values
Histoplasma/Blastomyces Antigen Result:
Not Detected
Histoplasma/Blastomyces Antigen Value:
Not Detected: 0.0 ng/mL
Detected: <1.3 ng/mL
Detected: 1.3-20.0 ng/mL
Detected: >20.0 ng/mL
Reference values apply to all ages.
Interpretation
Not detected:
No antigen from Histoplasma or Blastomyces detected. False-negative results may occur depending on extent of disease or site of infection. Repeat testing on a new specimen if clinically indicated.
Detected:
Antigen from Histoplasma or Blastomyces (unable to differentiate) was detected, below the limit of quantification (<1.3 ng/mL). Result should be correlated with clinical presentation, exposure history, and other diagnostic procedures, including culture, serology, histopathology, and radiographic findings to aid in the differentiation between histoplasmosis or blastomycosis.
Detected:
Antigen from Histoplasma or Blastomyces (unable to differentiate) detected. Result should be correlated with clinical presentation, exposure history, and other diagnostic procedures, including culture, serology, histopathology, and radiographic findings, to aid in the differentiation between histoplasmosis and blastomycosis.
Detected:
Antigen from Histoplasma or Blastomyces (unable to differentiate) detected, above the limit of quantification (>20.0 ng/mL). Result should be correlated with clinical presentation, exposure history, and other diagnostic procedures, including culture, serology, histopathology, and radiographic findings, to aid in the differentiation between histoplasmosis or blastomycosis.
Method Description
The assay detects Blastomyces dermatitidis antigen in human serum samples using specific, proprietary antibodies in an enzyme-linked immunosorbent assay format. The detection method involves an enzyme/substrate system with the level of urinary B dermatitidis antigen proportional to the assay signal. The patient specimen result is compared to a cutoff calibrator and a standard curve of a series of assay calibrators (1.25 to 20.00 ng/mL) to determine the presence or absence of antigen and, if present, to establish a quantitative level of B dermatitidis serum antigen.(Package insert: Blastomyces dermatitidis Urinary Antigen Detection Kit. Gotham Biotechnology; V1, R3, 06/2021)
Day(s) Performed
Monday through Sunday
Report Available
Same day/1 to 3 daysSpecimen Retention Time
14 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester
CPT Code Information
87449
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| UHBAG | Histoplasma/Blastomyces Ag, EIA, U | 105123-4 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| UHBAR | Histoplasma/Blastomyces Ag Result | 104871-9 |
| DEXBH | Histoplasma/Blastomyces Ag Value | 104872-7 |