Home
HelpTest Code LAB12967 CYP3A5 for Tacrolimus Metabolism
Method Description
The CYP3A5 gene encodes an enzyme with a strong pharmacogenetic association for metabolism of tacrolimus, an immunosuppressant commonly prescribed following solid organ transplant. Genomic DNA is extracted from the whole blood. Clinically relevant variants in CYP3A5 including functional (*1) and tier 1 non-functional alleles (*3, *6, and *7) are interrogated using whole genome SNP microarray Global Diversity Array (GDA) chip with enhanced pharmacogenetic content (Illumina, Inc).
Collection:
Specimen: Peripheral Blood; Whole Blood
Container: Lavender Top Tube (EDTA)
Volume: 3ml
Instructions: Invert several times to mix blood and anti-coagulant to prevent clotting.
Storage Instructions:
Send specimen to the lab immediately after collection. Specimens can be shipped at room temperature. If temperature exceeds 90oF use refrigerated coolant.
Turnaround Time (TAT):
Results are reported within 8 days
Test Availability:
Test is performed in batches twice a week.