Test Code LAB1091 Riboflavin (Vitamin B2), Plasma
Additional Codes
VITB2
Secondary ID
42363Useful For
Evaluation of individuals who present the signs of ariboflavinosis
Method Name
Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)
Portions of this test are covered by patents held by Quest Diagnostics
Specimen Type
Plasma HeparinShipping Instructions
Ship specimen in amber vial to protect from light.
Specimen Required
Patient Preparation:
Fasting: 12 hours, required; Infants should have specimen collected before next feeding
Supplies: Amber Frosted Tube, 5 mL (T915)
Collection Container/Tube:
Preferred: Green top (sodium or lithium heparin)
Acceptable: Light-green top (sodium or lithium heparin plasma gel)
Submission Container/Tube: Amber vial
Specimen Volume: 2 mL plasma
Collection Instructions: Within 2 hours of collection, centrifuge and aliquot plasma into an amber vial.
Specimen Minimum Volume
Plasma: 0.5 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Plasma Heparin | Refrigerated (preferred) | 28 days | LIGHT PROTECTED |
| Frozen | 28 days | LIGHT PROTECTED | |
| Ambient | 72 hours | LIGHT PROTECTED |
On-campus collections: Tube to 99 or deliver to University Extension Hospital Room EH318
Submission Container/Tube: Amber vial, Refrigerated
.
Off-campus collections: Protect from light
Centrifuge within 2 hours of collection and aliquot to amber vial.
Specimen to be stored/transported Refrigerated
Reject Due To
| Gross hemolysis | OK |
| Gross lipemia | Reject |
| Gross icterus | OK |
Reference Values
1-19 mcg/L
Interpretation
Low concentrations in the plasma are indicative of nutritional deficiency. Concentrations below 1 mcg/L are considered significantly diminished. Marginally low levels probably represent nutritional deficiency that should be corrected.
Method Description
Riboflavin (vitamin B2) is extracted from plasma specimens with internal standard and then analyzed by liquid chromatography tandem mass spectrometry.(Unpublished Mayo method)
Day(s) Performed
Monday, Wednesday, Friday
Report Available
2 to 5 daysSpecimen Retention Time
2 weeksPerforming Laboratory
Mayo Clinic Laboratories in Rochester
CPT Code Information
84252
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| VITB2 | Riboflavin (Vitamin B2), P | 2924-9 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 61637 | Riboflavin (Vitamin B2), P | 2924-9 |