Test Code CYSTG Cysticercosis (Taenia solium), IgG, Serum
Specimen Required
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 0.5 mL
Collection Instructions: Centrifuge and aliquot serum into plastic vial.
Secondary ID
616730Useful For
Aid for the diagnosis of cysticercosis caused by infection with Taenia solium
Method Name
Enzyme-Linked Immunosorbent Assay (ELISA)
Specimen Type
SerumSpecimen Minimum Volume
0.4 mL
Specimen Stability Information
Specimen Type | Temperature | Time | Special Container |
---|---|---|---|
Serum | Refrigerated (preferred) | 14 days | |
Frozen | 30 days |
Reject Due To
Gross hemolysis | Reject |
Gross lipemia | Reject |
Heat-inactivated specimen | Reject |
Reference Values
Negative
Reference values apply to all ages.
Interpretation
Positive:
Antibodies to Taenia solium (cysticercosis) detected. Confirmatory testing through the Centers for Disease Control and Prevention is recommended. False-positive results may occur in patients with other helminth infections.
Negative:
No antibodies to T solium (cysticercosis) detected. A negative result may not rule-out infection as the sample may have been collected prior to the development of a detectable level of antibodies. Sensitivity is negatively impacted by the presence of few cysticerci or location in areas less accessible to the immune system. Repeat testing on a new sample is recommended for patients at high risk of cysticercosis.
Method Description
The kit provides all the material needed to perform 96 enzyme-linked immunosorbent assays (ELISA) on breakable microtitration wells sensitized with Taenia solium cyst soluble antigens. Specific antibodies in the sample will bind to these antigens and washing will remove unspecific antibodies. The presence of parasite specific antibodies is detected with a protein A - alkaline phosphatase conjugate. A second washing step will remove unbound conjugate. Revealing bound antibodies is made by the addition of p-nitrophenyl phosphate (pNPP) substrate, which turns yellow in the presence of alkaline phosphatase. Color intensity is proportional to the amount of T solium specific antibodies in the sample. Potassium phosphate is added to stop the reaction. Absorbance at 405 nm is read using an ELISA microplate reader.(Package insert: Taenia solium Enzyme immunoassay for the diagnosis of human cysticercosis. Bordier Affinity Products SA; 04/2018)
Day(s) Performed
Tuesday
Report Available
1 to 7 daysSpecimen Retention Time
14 daysPerforming Laboratory
Mayo Clinic Laboratories in RochesterCPT Code Information
86682
LOINC Code Information
Test ID | Test Order Name | Order LOINC Value |
---|---|---|
CYSTG | Cysticercosis (T. solium), IgG, S | 56485-6 |
Result ID | Test Result Name | Result LOINC Value |
---|---|---|
CYSTG | Cysticercosis (T. solium), IgG, S | 56485-6 |