Sign in →

Test Code CRT2F Creatinine, 24 Hour, Urine


Specimen Required


Only orderable as part of a profile. For more information see:

-TLTE4 / Leukotriene E4, 24 Hour, Urine

-MCM24 / Mast Cell Mediators, 24 Hour, Urine


Secondary ID

618161

Useful For

Normalizing urinary analytes to account for the variation in urinary concentration

Method Name

Only orderable as part of a profile. For more information see:

-TLTE4 / Leukotriene E4, 24 Hour, Urine

-MCM24 / Mast Cell Mediators, 24 Hour, Urine

 

Enzymatic Colorimetric Assay

Specimen Type

Urine

Specimen Minimum Volume

1 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Urine Frozen (preferred) 30 days
  Refrigerated  30 days
  Ambient  14 days

Reject Due To

All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.

Reference Values

Only orderable as part of a profile. For more information see:

-TLTE4 / Leukotriene E4, 24 Hour, Urine

-MCM24 / Mast Cell Mediators, 24 Hour, Urine

 

Normal values mg per 24 hours:

Males: 930-2955 mg/24 hours

Females: 603-1783 mg/24 hours

 

Reference values have not been established for patients who are younger than 18 years.

Interpretation

Decreased creatinine clearance indicates decreased glomerular filtration rate. This can be due to conditions, such as progressive kidney disease, or result from adverse effect on renal hemodynamics that are often reversible, including certain drugs or from decreases in effective renal perfusion (eg, volume depletion or heart failure).

 

Increased creatinine clearance is often referred to as "hyperfiltration" and is most frequently seen during pregnancy or in patients with diabetes mellitus before diabetic nephropathy has occurred. It may also occur with large dietary protein intake.

Method Description

This enzymatic method is based on the determination of sarcosine from creatinine with the aid of creatininase, creatinase, and sarcosine oxidase. The liberated hydrogen peroxide is measured via a modified Trinder reaction using a colorimetric indicator. Optimization of the buffer system and the colorimetric indicator enables the creatinine concentration to be quantified both precisely and specifically.(Package insert: Creatinine plus ver 2. Roche Diagnostics; V 15.0, 03/2019)

Day(s) Performed

Monday through Sunday

Report Available

1 day

Specimen Retention Time

7 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

LOINC Code Information

Test ID Test Order Name Order LOINC Value
CRT2F Creatinine, 24 HR, U 65634-8

 

Result ID Test Result Name Result LOINC Value
CR_AF Creatinine, 24 HR, U 2162-6
TM10F Collection Duration (h) 13362-9
VL8F Urine Volume (mL) 3167-4
CRF24 Creatinine Concentration, 24 HR, U 20624-3