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HelpTest Code AC1Q Anti-C1q Antibodies, IgG, Serum
Specimen Required
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 0.5 mL
Collection Instructions: Centrifuge and aliquot serum into a plastic vial.
Secondary ID
621511Useful For
Evaluating patients with suspected anti-C1q vasculitis
Predicting renal involvement in patients with systemic lupus erythematosus
Detection of anti-C1q antibodies in serum
Method Name
Enzyme-Linked Immunosorbent Assay (ELISA)
Specimen Type
SerumSpecimen Minimum Volume
0.4 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum | Refrigerated (preferred) | 21 days | |
| Frozen | 21 days |
Reject Due To
| Gross hemolysis | Reject |
| Gross lipemia | Reject |
| Gross icterus | Reject |
Reference Values
<20 U/mL (Negative)
20-39 U/mL (Weak Positive)
40-80 U/mL (Moderate Positive)
>80 U/mL (Strong Positive)
Interpretation
A positive result for Anti-C1q antibodies may support a diagnosis of anti-C1q vasculitis or renal involvement in patients with systemic lupus erythematosus in the appropriate clinical context.
A negative result indicates no detectable IgG antibodies to C1q and does not rule out a diagnosis.
Method Description
Testing for antibodies to C1q is accomplished using a laboratory-developed immunoassay.(Unpublished Mayo method)
Day(s) Performed
Wednesday
Report Available
2 to 8 daysSpecimen Retention Time
2 weeksPerforming Laboratory
Mayo Clinic Laboratories in Rochester
CPT Code Information
83520
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| AC1Q | Anti-C1q Antibodies, IgG, S | 44702-9 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| AC1Q | Anti-C1q Antibodies, IgG, S | 44702-9 |