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HelpTest Code LAB39 Vancomycin, Trough
Notes:
SAMPLING TIME – TROUGH: Draw within 1 hr of next dose
Collection:
Specimen: Blood
Preferred: Lt Green w/ Gel - Li Hep
Acceptable: Serum Separator or Plain Red tube.
Specimen Volume: 5 mL; Minimum 1 mL
Pediatric Collection:
One Lt Green w/ Gel - Li Hep, SST, or Red Top microtainer filled to 600 uL.
Stability:
Once serum/plasma is separated from cells:
Ambient: 8 Hours
Refrigerated (preferred): 1 Week
Frozen: 2 Weeks
Turn Around Time (TAT):
STAT: 1 HOUR
Routine: 4 HOURS
Test Availability:
24 hours a day / 7 days a week
Reference Interval:
Therapeutic levels may vary according to the patient’s age, renal function, and severity of the infection.
Therapeutic Trough: 10.0 – 20.0 mcg/mL
Therapeutic Peak: 20.0 – 40.0 mcg/mL
Random: No extablished reference range
Interpretive Data:
The Abbott ALINITY cSystem particle-enhanced turbidimetric inhibition immunoassay (PETINIA) is used to perform this assay. Results obtained with other methods cannot be used interchangeably. Reference range adapted from Lexi-Comp’s Drug Information Handbook 13th Edition. This assay is FDA-approved for serum and plasma only. Testing other biological fluids has not been validated. Serum/plasma reference ranges do not apply to other sample types. Interpret with caution. Effective 9/24/2009, the vancomycin trough therapeutic range is changed to 10-20 mcg/mL based on recomendation published in AM J. Health-Syst Pharm 2009 66:82 and at the request of the Hospital’s Anti-Infective Subcommittee.
Additional Test Codes
VANCO T
Performing Laboratory Section
Chemistry / UMC MAIN LABORATORY