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HelpTest Code LAB2562 Cystatin C with EGFR
Additional Codes:
CYSTCG
Collection:
Specimen: Blood
Container: Serum Separator, Plain Red Top Tube, Green Lithium Heparin with gel
Volume: 4 mL; Minimum 2 mL
Pediatric Collection:
Two Gold, Green, or Red microtainers filled to 600 uL.
Storage Instructions:
Serum should be separated from red cells when stored or shipped. Specimens that cannot be tested immediately can be refrigerated up to 7 days. Freeze specimens for extended storage.
Turnaround Time (TAT):
Reported same day as performed.
Test Availability:
Test performed Monday, Wednesday, Thursday.
Performing Laboratory Section:
Special Chemistry / UMC Main Laboratory
Send To:
UMC MAIN LABORATORY Specimen Receiving – EH319 Hospital Extension
Reference Interval:
0 - 18 years - No reference range
>18 years - 0.56 - 0.99 mg/L
Interpretive Data:
Serum cystatin C is measured by an immunoturbidimetric assay (Optilite, The Binding Site). Results by other assays should not be used interchangeably due to differences in analytical methods. Cystatin C is a 13kDa, non-glycosylated endogenous cysteine protease inhibitor that is produced by all nucleated cells at a constant rate. It is freely filtered by the glomerulus, and is almost completely reabsorbed and degraded by the proximal tubular cells. The production rate of cystatin C is not affected by age, gender, muscle mass or inflammatory processes, making serum cystatin C an ideal marker of glomerular filtration rate (GFR). A reduction in the GFR results in an increase in cystatin C concentrations. Cystatin C has been shown to be superior to creatinine as marker for GFR. The serum cystatin C reference interval is for adults only. No reference intervals are established for individuals under 18 years old.